Iran has established a chokehold on the Strait of Hormuz, through which a fifth of the world’s traded oil passed in peacetime, after the U.S. and Israel attacked Iran on Feb. 28. Ship traffic through the waterway has slowed to a trickle, roiling the global economy and spiking prices for energy and other goods across the world.

U.S. Air Force retired Gen. Philip Breedlove, a former NATO commander, speaks to Fox News Digital about the relationship between the Russian and Iran, and how the U.S. war in Iran is becoming a "test of will.

President Donald Trump had warned after Tuesday's U.S. strikes that any retaliation would see Iran "hit again at a much harder and higher level."

President Trump called on Iranians to “rise up and fight” on Tuesday as the United States seems increasingly bogged down after six months of conflict.

The Iranian Red Crescent says the deaths happened when shrapnel from a US missile hit a home where a celebration was taking place in southern Iran.

Iran and its Arab neighbours were plunged back into war on Wednesday by the biggest exchange of fire between Tehran and Washington since July, with U.S. forces striking Iran's southern coast and Iran firing at American bases across the region.

Iran said the latest attacks killed several civilians, including a child, while the U.S. military said it “never targets civilians.”

The strikes follow attacks against commercial shipping and service members.