Adults with obesity who took a once-daily pill called orforglipron lost an average of 11.2% of their body weight over 72 ...

A new once-daily weight-loss pill called orforglipron delivered better weight loss and blood sugar improvements than the ...

GLP-1s, or glucagon-like peptide-1 receptor agonists, are a class of medications primarily used in the management of type 2 ...

Tirzepatide is the active ingredient in an injectable medication (Zepbound) approved by the U.S. Food and Drug Administration (FDA) to treat obesity and overweight in adults with other weight-related ...

Contrave and phentermine are weight loss medications approved by the U.S. Food and Drug Administration (FDA) for adults with obesity or adults with overweight and a weight-related medical condition.

New research presented at the European Congress on Obesity (ECO 2026) in Istanbul, Turkey (12–15 May) and published in The Lancet shows that people who have lost weight using the maximum tolerated ...

"By contrast, we show that rapid weight loss is not associated with weight regain, and, more importantly, that a larger proportion of participants undergoing rapid weight loss—compared with gradual ...

Retatrutide met primary and key secondary endpoints in a 2339-participant, randomized, double-blind, placebo-controlled phase 3 trial, demonstrating clinically meaningful weight reduction across 4, 9, ...

If you’re on a weight loss journey, it can be easy to look for instant results – but the most successful weight loss journeys are rarely dramatic… One of the biggest problems in weight loss today is ...