The Binding of Isaac: Rebirth has straightforward controls, which players can view by selecting Options from the Main Menu and then choosing Controls. However, the Controls menu cannot be opened ...

Learn how to see what items do in The Binding of Isaac, including passive collectibles and active items like cards, runes, and pills.

Sam is a guide writer for GameRant, as well as an independent game designer. Sam loves horror games most of all when it comes to making and playing. She however plays games from all genres and loves ...

William Parks is a Game Rant editor who specializes in puzzle games, indie releases, Nintendo titles, and completion-focused guide coverage. Since joining Game Rant in 2019, he has written and edited ...