A protein that's essential to every cell's ability to turn off unnecessary genes is well known for its key function of compacting genes and its connection to cancer when it undergoes mutation. But ...

The first full-length structures of two heat shock chaperone proteins in a complex reveal the key structural region regulating their function, according to a new study from St. Jude Children's ...

A short serine-rich disordered tail on the Listeria monocytogenes chaperone PrsA2 proves essential for folding the toxin ...

Plasmodium falciparum relies on a sophisticated network of molecular chaperones to navigate the extreme environmental transitions between mosquito vector and human host. Central to this system are ...

Proteins are how cells get work done. They carry out nearly every important cellular task, from ferrying messages to controlling which genes are turned on or off. And in order for proteins to perform ...

The first full-length structures of two heat shock chaperone proteins in a complex reveal the key structural region regulating their function, according to a new study from St. Jude Children's ...

Proteins control most of the body's functions, and their malfunction can have severe consequences, such as neurodegenerative diseases or cancer. Therefore, cells have mechanisms in place to control ...

Heat shock protein 70 chaperones exert neuroprotective effects by preventing aggregation and regulating the proteostasis of pathological protein via its degradation. Neurodegenerative diseases such as ...

A team of researchers from the College of Natural Sciences is the first to show how proteins called “chaperones” are vital in ensuring that neurons can transmit signals to one another. When this ...

COLUMBUS, Ohio – A protein that’s essential to every cell’s ability to turn off unnecessary genes is well known for its key function of compacting genes and its connection to cancer when it undergoes ...