There is a huge amount of DNA in most human cells, and that DNA has to be carefully compacted and organized so that it will ...

New ultra-detailed imaging exposes the hidden structure and behavior of chromatin condensates — and hints at how their failures may drive disease.

Study finds CRISPR/Cas gene editing causes “chromatin fatigue” – another surprise mechanism by which it can produce unwanted ...

Over the past few decades, advances in hematology have illuminated how a delicate balance between stem cell self-renewal and ...

CTCF is widely recognized for its essential role in mediating chromatin loops to regulate gene expression, particularly by ...

The developmental period is a critical window during which environmental cues interact with the genome to shape lifelong trajectories of health and disease.

Classical dendritic cells (cDCs) are essential for immune responses and differentiate from hematopoietic stem cells via intermediate progenitors, such as monocyte–DC progenitors (MDPs) and common DC ...

Over the past few decades, advances in hematology have illuminated how a delicate balance between stem cell self-renewal and ...

Inside every human cell, six feet of DNA folds into a nucleus that is only a few micrometers wide, yet still manages to ...

Myelodysplastic syndrome (MDS) arises from defective blood stem cells that progressively lose their normal functions.