A new review explores how advances in understanding X chromosome inactivation (XCI) are creating potential therapeutic opportunities for a range of X-linked genetic disorders, including Rett syndrome, ...

In a study published in the journal Science, researchers in Queensland and the United States discovered that the human X chromosome attracts an unusual kind of DNA mutation, potentially doubling the ...

Ring chromosome disorders encompass rare structural chromosomal aberrations in which terminal segments are lost and the remaining arms fuse to form a circular chromosome. Such rearrangements often ...

Human DNA, which is approximately two meters in length, is organized into a compact, thread-like structure known as the chromatin, so it could fit into the nucleus, a tiny sphere that’s only about six ...

Human sex chromosomes originated from a pair of autosomes, the ordinary or non-sex chromosomes that contain the majority of our genome and come in identical pairs. That ancestral pair of autosomes ...