Does prolonged mitosis in cells depleted of CHC represent an alternative function of clathrin or an indirect effect of inhibiting clathrin-mediated endocytosis? To investigate this question a dominant ...

Cell membranes are arranged into various lipid assemblies, such as regions that are rich in a particular phosphoinositide and lipid-raft microdomains. The latter are assemblies of cholesterol and ...

(Phys.org)—The base-pairing properties of DNA, combined with our abilities to create synthetic DNA in the laboratory have led to advances in nanoscale architecture and molecular device designs. Less ...

In clathrin-mediated endocytosis, the cell membrane invaginates to take up metabolites, hormones, and proteins from the cell surface into intracellular vesicles. Cells employ several pathways for ...

A protein called "clathrin," which is found in every human cell and plays a critical role in transporting materials within them, also plays a key role in cell division, according to new research at ...

Newly published research by Indiana University structural biologist Joel Ybe and colleagues identifies a "topology switch" in the protein clathrin, the function of which may shed light on molecular ...

Clathrin coated pits (CCPs) are spherical, cage-like structures located on the plasma membrane that are responsible for receptor-mediated endocytosis. CCPs bud off the cell membrane with their ...

Clathrin mediated endocytosis (CME) at pre-synaptic terminals is functionally coupled to neuro-transmitter release. Like other cytosolic proteins, clathrin is synthesized in cell-bodies and conveyed ...

Clathrin proteins involved in endocytosis form a lattice that can dramatically change its shape Combination of fluorescence microscopy and 3D electron microscopy allows quantitative data to be ...

Endocytosis is the process by which cells take in molecules from their surroundings. Clathrin-dependent endocytosis requires the recruitment of clathrin to help curve the plasma membrane into the ...

The discovery, featured on the cover of the Journal of Cell Biology in August, sheds light on the process of cell division and provides a new angle for understanding cancer. Without clathrin, cells ...

In a article in the Proceedings of the National Academy of Sciences, Prof Mike Dustin and his research team have explained how messages are passed across the immunological synapse. The research could ...