Isaac TeSlaa must step up for the Detroit Lions to pull off a road upset against the Buffalo Bills in Week 2. Athlon Sports Buffalo Bills Impact Rookie Handed Concerning Take Ahead of Lions Game The Buffalo Bills could make a clear decision on an impact rookie in Week 2 against the Detroit Lions on Thursday Night.

Isiah Pacheco will miss the Detroit Lions' exhibition opener this week against the Cincinnati Bengals − and maybe the rest of the preseason − with a knee injury.

Detroit Lions tight end Sam LaPorta returned to practice on Tuesday after missing about a week due to a hip injury issue.

The Detroit Lions have ended their relationship with center Michael Niese, waiving the 28-year-old from injured reserve with an injury settlement, via ESPN’s NFL transaction log.

Campbell said Izien was ahead of schedule in his recovery from a groin injury suffered in the second preseason game. The versatile defensive back is the only player listed on the team's game designations ahead of Sunday afternoon's season opener,

The Detroit Lions host the Washington Commanders for their second preseason game on Saturday, Aug. 22, at Ford Field.