Lions rule out starting offensive linemen Blake Miller and Christian Mahogany against Bills The Detroit Lions will be without two starting offensive linemen against the Buffalo Bills on Thursday night. Detroit ruled out rookie offensive tackle Blake Miller ...

A new era will begin in Buffalo when the Bills host the Detroit Lions on Thursday night. The new Highmark Stadium will play host to its first regular-season game, as the Bills said goodbye to their previous home for 53 seasons at the end of the 2025 season.

The Buffalo Bills kick off Week 2 of the NFL season with a home opener in their new stadium Thursday night. CBS Sports NFL analyst Mike Renner has more.

The Buffalo Bills host the Detroit Lions on Thursday, Sept. 17. Here's how to stream the game live on Amazon Prime.