New study identifies CAR3 as a key osteoblast protein promoting collagen mineralization, bone formation, and skeletal ...

Gestational growth and development of bone is an understudied process compared to soft tissues and has implications for lifelong health. This study investigated growth and development of human fetal ...

Osteoarthritis (OA) is a degenerative joint disease affecting millions of people worldwide 1. It is characterized by chronic pain that leads to disability, and loss of joint motion, thus reducing ...

Skeletal stem cells (SSCs) are essential for bone development, homeostasis, and repair. Recent studies have identified distinct SSC populations in long bones, craniofacial bones, and spine. Techniques ...

New study identifies CAR3 as a key osteoblast protein promoting collagen mineralization, bone formation, and skeletal ...

Blood cancers such as leukemia are caused by genetic changes in the blood-forming stem cells of the bone marrow. Scientists at the University Medical Center Mainz have now shown how chronic ...

Rather than completely blocking all downstream signals, the peptide developed in this study focuses on inhibiting the activation of p38-MAPK. This is enough to downregulate the development of mature ...

If you have ever broken a bone, you quickly learn two things: it hurts a lot, and bones are living tissue that takes time to heal, but they do heal. A fractured femur, for instance, may take six ...

The first 'blueprint' of human skeletal development reveals how the skeleton forms, shedding light on the process of arthritis, and highlighting cells involved in conditions that affect skull and bone ...

As our bodies age, our bones break down, raising our risk of osteoporosis — a condition that makes our skeletal scaffolding brittle and increases the likelihood of fractures. Broken bones are ...