The respiratory epithelium forms a continuous lining from the nasal vestibule to the distal alveoli, acting as both a physical barricade against inhaled particles and a dynamic immunological interface ...

With a length of around eight meters and its countless finger-shaped protrusions, known as villi, the intestine represents the largest contact surface in the inner of our body that comes in contact ...

The small airways serve as a primary line of defense against inhaled particles and facilitate gas exchange by directing air to the alveoli. These small airways are critical in the pathophysiology of ...

A research team led by scientists from the State University of Campinas (UNICAMP) in São Paulo, Brazil, has made significant progress in understanding the relationship between gut microbiota and ...

Normal epithelial cells show the ability to push out precancerous ones present in the epithelium, by means of 'cell competition.' But the exact molecular mechanism of this recognition by normal ...

Crypt-base-columnar cells are continuously dividing intestinal stem cells that generate IECs, which are composed by distinct specialised cell types that play different functions: Enterocytes (in the ...

Deep in the folds of the intestine, in microscopic pockets called crypts, a quiet surveillance system is always at work. Stem cells lining the gut wall are not just rebuilding tissue—they are ...