The Bills have elevated RB Frank Gore Jr. and WR Greg Dortch from the practice squad for tonight's game against the Lions. Gore is likely a one-for-one replacement for third-down running back Ty Johnson, who was limited at practice all week with a hamstring injury. Johnson has been dealing with the injury for over a month.

The SportsLine projection model has revealed its Detroit vs. Buffalo picks for NFL Week 2 on Thursday, Sept. 17 as Highmark Stadium hosts its first regular-season game

The Detroit Lions are back in the national spotlight, with a marquee matchup to open a brand-new stadium in Buffalo on Thursday night.

After Detroit's dramatic overtime win to open the season, there are plenty of quotes from inside the locker room with the Lions and New Orleans Saints.

The Lions visit the Bills in Week 2 of the 2026 NFL season. Here's your full game preview, prediction, and how to watch live on DAZN.

Blake Miller's NFL debut was a major headline in the Detroit Lions Week 1 win over the New Orleans Saints.

The Lions held off a go-ahead two-point attempt on the final play of overtime to steal a 31-30 victory Sunday against the Saints.