How to Bet On Detroit Lions Game Tonight

Get Up to $365 Bonus Lions-Bills TNF

How to bet Lions-Bills on 'TNF': Analysis, tips and favorite plays

"Thursday Night Football" features the Buffalo Bills hosting the Detroit Lions in the first regular-season game at the new Highmark Stadium.

· 7h

Bills-Lions Thursday Night Football odds, betting: 1 bettor has $1 million wager on Lions

· 6h

How, where to bet on NFL Week 2: Best online betting apps, nearly $4,000 sportsbook promos for Lions-Bills TNF

· 7h

Lions vs. Bills score, live updates: Josh Allen’s passing TD extends Buffalo lead to 14-0

Follow our live coverage as Josh Allen and Buffalo host Jared Goff and Detroit in an NFL primetime game.

· 1d

Bills set to open new stadium hosting the Lions in a prime-time matchup

· 5h

Ben Sawyer leaves job as New Zealand women's head coach after review

· 8h

Thursday Night Football live updates: Bills vs Lions start time, TV channel tonight

Brady was promoted to head coach this offseason after serving as the Bills' offensive coordinator, and his debut produced an explosive 36-31 victory over the Texans.

· 15h

How to watch Detroit Lions vs. Buffalo Bills game for NFL Week 2

· 5h

NZ Rugby set for pivotal meeting after damning report lists financial challenges

17h

Best NFL Picks and Predictions Today (How to Bet Lions vs. Bills on Thursday Night Football in NFL Week 2)

Thursday Night Football in the 2026 season is off to an insane start. After the NFL treated us to a San Francisco 49ers vs. Los Angeles Rams battle in Week 1, i

11hon MSN

Bills vs Lions odds, Expert picks, team and player news, betting trends, and stats

Buffalo Bills vs Detroit Lions Game Preview