The Bills have elevated RB Frank Gore Jr. and WR Greg Dortch from the practice squad for tonight's game against the Lions. Gore is likely a one-for-one replacement for third-down running back Ty Johnson, who was limited at practice all week with a hamstring injury. Johnson has been dealing with the injury for over a month.

The spotlight is on the Buffalo Bills' home opener and the first regular-season game at the new Highmark Stadium, but the matchup itself could be just as memorable. Buffalo and Detroit both opened the season with high-scoring victories in Week 1 while showcasing explosive offenses led by quarterbacks Josh Allen and Jared Goff.

The Lions aren't dead yet.

The Lions elevated two offensive linemen to handle their Week 2 injury issues and officially brought Levi Onwuzurike back after last weekend's roster maneuvering.

The Detroit Lions will play their first game on the road for the 2026 season tonight against the Buffalo Bills at Highmark Stadium. Looking to watch the game from home? We’ve got all the information you’ll need to be ready for kickoff.