MSP: Methylation-specific PCR; MSRE: Methylation-sensitive restriction endonucleases; QMSP: Quantitative, methylation-specific PCR; X: Methylation associated with prognosis. Mohammad Obaidul Hoque, ...

The prostate is the single organ most frequently afflicted by cancer in men. Prostate cancer affects approximately 4 million American men, with another 330,000 men expected to be diagnosed with the ...

MASPIN ("tumor suppressor shield"): MASPIN is a natural defense protein that blocks tumor invasion, regulates cell migration and angiogenesis, promotes apoptosis, and enhances treatment sensitivity.

CDKN2A is one of the body's most important natural defenses against cancer. Often called the "cell cycle brake," this gene tells cells when to stop dividing and helps damaged cells self-destruct. In ...

Contemporary diagnosis of very low risk prostate cancer in a multi-centered hospital system. Use of the Prostatype P-score to predict adverse pathology (AP) at radical prostatectomy (RP). This is an ...

Personalized Therapy Selection by Integration of Molecular Cancer Classification by the 92-Gene Assay and Tumor Profiling in Patients With Cancer of Unknown Primary Detectability by Gleason grade ...

Epigenetic changes can cause prostate cancer to resist treatment by switching genes on or off. One epigenetic mechanism tags genes with DNA methylation marks. This process is mediated by molecules ...

New epigenetic biomarkers to predict more aggressive forms of prostate cancer have been discovered. New epigenetic biomarkers to predict more aggressive forms of prostate cancer have been discovered ...