Sexual reproduction begins with sperm–oocyte fusion to form a zygote, where chromatin undergoes dramatic reorganization to establish totipotency. Although nucleosomes- the basic units of eukaryotic ...
The rapid growth of single-cell transcriptomic technology has produced an increasing number of datasets for both embryonic development and in vitro pluripotent stem cell-derived models. This avalanche ...
Illustration of an embryo in the early stages of development. (Design Cells/iStock/Getty Images) The first moments of life ...
The team mapped the spatial and temporal patterns of glucose uptake using single-cell-resolution imaging of developing mouse embryos, stem cell models, and embryo-derived tissues. They found that the ...
Protein modifications are key to cell survival because they ensure they do what they are supposed to do in a healthy system. One vital modification involves adding sugar molecules to proteins, a ...