A series of recent studies in mice and rats has mapped specific brain circuits that appear to drive chronic pain, identifying ...

In A Nutshell Stanford researchers traced a brain circuit loop, running from the spinal cord up through the brain and back ...

Scientists have discovered a brain circuit that gives pain its emotional sting, explaining why some hurts linger as suffering. The breakthrough challenges our beliefs about how we process pain and may ...

Salk scientists uncover a key neural circuit in mice that gives pain its emotional punch, opening new doors for treating fibromyalgia, migraine, and PTSD LA JOLLA (July 9, 2025)—Pain isn’t just a ...

Four tiny 3D organs connected themselves in a lab dish, forming a replica of the human pain pathway, in a new study. The discovery allows scientists to better understand chronic pain and how pain ...

Researchers integrated four organoids that represent the four components of the human sensory pathway, along which pain signals are conveyed to the brain. Stimulation of the sensory organoid (top) by ...

So when you touch a hot stove, the nerve endings in your fingers react instantly. But the ouch comes a split-second later, when that information finally reaches your brain. Well, now, scientists have ...

A research team funded by the National Institutes of Health (NIH) has developed a medication that shows promise in treating acute and chronic pain. The drug, known as VIP36, targets the body’s ...

People’s mindsets can affect their experience of pain. For example, a soldier in battle or an athlete in competition may report that an injury did not feel especially painful in the heat of the moment ...

Scientists have re-created a pain pathway in the brain by growing four key clusters of human nerve cells in a dish. This laboratory model could be used to help explain certain pain syndromes, and ...