A single human gene can produce multiple protein isoforms through alternative splicing, greatly expanding the functional diversity of the proteome.

Researchers headed by a team at the Centre for Genomic Regulation, Barcelona Institute of Science and Technology and at the Wellcome Sanger Institute have developed an AI tool that they say has made a ...

Researchers developed a new machine learning method that, given a relevant amino acid sequence, can automatically predict the location of a protein in any human cell line down to the single-cell level ...

AI systems have recently had a lot of success in one key aspect of biology: the relationship between a protein’s structure and its function. These efforts have included the ability to predict the ...

Proteins sourced from microorganisms are attracting attention for their potential in biomanufacturing a variety of products, including pharmaceuticals, industrial enzymes, and diagnostic antibodies.

In the living world, roughly a third of all proteins we know rely on metals to function. Zinc helps enzymes break down molecules, iron helps carry oxygen in the blood, calcium helps relay signals in ...

The search space for protein engineering grows exponentially with complexity. A protein of just 100 amino acids has 20^100 possible variants-more combinations than atoms in the observable universe.