Subcellular lipid composition and transport significantly influence the physiological and pathological functions of both cells and organelles. However, lipid transport and turnover between organelles ...

A recent report published in the STAR Protocols journal depicted a protocol for an antibody-based proximity labeling to discover biotinylated interactors of severe acute respiratory syndrome ...

More powerful than previous methods, a new approach for tagging and harvesting DNA-associated proteins from cells could open deeper insights into transcription control. Gene transcription requires a ...

Tumor immunotherapies, especially those leveraging T cells to identify and eliminate cancer cells, represent a major breakthrough in cancer treatment. However, many tumor-associated antigens are too ...

The body's organs are in constant communication. Fat tissue tells the liver when to store or release energy, the immune system signals localized inflammation, and thousands of proteins carry these ...

(Nanowerk News) Researchers have created a new nanometer-scale proximity labeling system that targets histidine residues quickly, providing a new chemical tool in protein chemical modification. The ...

A team of researchers from the University at Buffalo in Amherst, NY have successfully engineered a novel variant of streptavidin that forms a stable monomer and is capable of monovalent biotin ...