The 49ers are interested in trading for Bengals edge rusher Trey Hendrickson, but Cincinnati's 2025 aspirations are a huge hurdle for SF.

The San Francisco 49ers are in the midst of a major injury crisis, entering Sunday’s game against the Tampa Bay Buccaneers with a depleted roster missing starters Brock Purdy, George Kittle, Brandon Aiyuk,

Sunday Night Football heads to the West Coast in Week 7 when the Atlanta Falcons (3-2) visit the injury-riddled San Francisco 49ers (4-2). This is SNF’s first trip to Levi’s Stadium this season, which will host Super Bowl LX on NBC on February 8, 2026.

OT Trent Williams addresses Jauan Jennings injuries after Buccaneers loss, sending a blunt message playing through pain.

The San Francisco 49ers (4-1) beat the Los Angeles Rams (3-2) by a final score of 26-23 on Thursday Night Football when Kyren Williams was stopped on a fourth and short in overtime, but before that play Williams fumbled on the goal line to give the game to SF,

The San Francisco 49ers are 4-1 and currently lead the NFC West. But they have a tough matchup on Sunday when they travel to Tampa to face the 4-1

It's hard to imagine a more remarkable start to a 49ers career than what kicker Eddy Pineiro has had in his first month with the red and gold. For the second time, Pineiro hit a game-winning field goal against a division rival, this time to help the injury ...

The San Francisco 49ers had lost another star to an injury, given up a fourth-quarter lead on a safety and were relying on a backup quarterback and a brand new kicker to maintain their perfect start to the season.

SNF Week 7 features Falcons at 49ers -- a crucial NFC matchup with many fantasy stars. Read about the best ATL vs. SF NFL DFS lineups for DraftKings and FanDuel GPP tournaments.