Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) activates apoptosis through the death receptors DR4 and DR5. Because of its superior safety profile and high tumor specificity ...
Structure of the TRAIL–DR5 complex reveals mechanisms conferring specificity in apoptotic initiation
EST database searching has led to the cloning and characterization of a number of proteins belonging to the tumor necrosis factor (TNF) and TNF receptor (TNF–R) families. Although structurally related ...
University of Pennsylvania researchers investigated death receptor 5 (DR5 or CD262) as a chimeric antigen receptor (CAR) target for solid tumors.
68Ga-HER2 affibody PET/CT imaging as an option in patients whose HER2 status of any tumor in the body needs to be deciphered. This is an ASCO Meeting Abstract from the 2021 ASCO Annual Meeting I. This ...
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