The 3′-untranslated region (3′UTR) of some vertebrate dystrophin genes shows an extraordinary degree and extent of conservation (better than that of many coding regions), a phenomenon that remains ...
Scientists may have uncovered a new way for cells to regulate protein expression. In the December 16 Neuron, researchers led by Mary Hynes at Rockefeller University, New York, reported that in mouse ...
The translational control of specific mRNAs is a prominent mechanism of gene regulation contributing to diverse physiological processes in many cell types. Although many features of a transcript can ...
Ribosomes, normally obedient to stop and start signals on messenger RNA, occasionally “go rogue.” They take it upon themselves to build proteins beyond the usual coding sequence, overrunning a portion ...
In what appears to be an unexpected challenge to a long-accepted fact of biology, researchers say they have found that ribosomes -- the molecular machines in all cells that build proteins -- can ...
Prognostication of survival from nasopharyngeal carcinoma by reduction of plasma Epstein-Barr viral DNA load at midpoint of radiotherapy course: A new paradigm of prognostication. This is an ASCO ...
When it comes to identifying cancer-driving mutations, research has focused almost exclusively on understanding how mutations in the coding region of genes may alter a protein’s function to promote ...
The dengue virus (DENV) is a single-stranded RNA virus with increasing worldwide prevalence causing severe mosquito-borne viral infections. Therefore, effective strategies to prevent and treat DENV ...
Since the COVID-19 pandemic, mRNA vaccines have gained attention as a next-generation pharmaceutical technology. mRNA therapeutics work by delivering genetic instructions that enable cells to produce ...
In what appears to be an unexpected challenge to a long-accepted fact of biology, Johns Hopkins researchers say they have found that ribosomes -- the molecular machines in all cells that build ...