2026 Week 1 NFL picks, best bets from proven model
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Ross Williams previews the first Sunday of the new NFL season and he's relying on Detroit Lions' ability to win big.
Our NFL betting guide tells you where to bet on NFL Week 1, while providing odds, betting trends, schedule, promo offers, and more
NFL Week 1 line movement, betting splits and injury news. See which sides moved through key numbers, and why, including the Vikings and Rams.
The spread shifted for a good set of reasons, and so should your betting slip. Throwing a banged-up offensive line in front of a tough Vikings defense on the road is a brutal way to start the year. Minnesota is healthier, tougher at home, and should cover. Cleveland Browns @ Jacksonville Jaguars (Jaguars -7.5 to Jaguars -9.0)
Week 1 of the NFL season has a rare double-digit favorite.
Spreads, Totals and Moneylines A plain English guide to reading NFL odds for Week 1. Spreads, moneylines, totals.
1don MSN
NFL odds: Week 1 parlays for favorites and underdogs include Eagles-Commanders, Broncos-Chiefs
SportsLine football expert Mike Tierney breaks down his favorite parlays for Week 1 of the NFL season