British Journal of Ophthalmology

Statin use is associated with lower risk of open-angle glaucoma incidence and treatment escalation

Background Retrospective cohort study using the TriNetX database to explore the relationship between statin use and glaucoma.
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False-positive patterns in optical coherence tomography in hyperopic and myopic eyes

Background/aims This study aimed to evaluate how axial length influences false-positive rates in ganglion cell analysis (GCA) and retinal nerve fibre layer (RNFL) maps and to identify distinct ...
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Evaluation of globe-preserving therapies in unilateral cT2/cT3 retinoblastoma: a multicentre study of 1566 eyes

1 State Key Laboratory of Eye Health, Department of Ophthalmology, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China Aims To evaluate survival, globe ...
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Corneal radius-specific axial length/corneal radius ratio cut-offs for improved myopia detection in children: a population-based study

1 Clinical Research Center, Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, School of Medicine, Tongji University, Shanghai Engineering Research Center of Precise ...
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Novel insights of minocycline as a neurovascular protective agent in retinitis pigmentosa

Background/aims Retinitis pigmentosa (RP) is characterised by progressive photoreceptor degeneration accompanied by vascular abnormalities. We have previously demonstrated that minocycline exhibits ...
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Semaglutide-associated NAION: a proposed ‘two-hit’ model involving buried optic disc drusen and sustained hypohydration

Semaglutide-associated non-arteritic anterior ischaemic optic neuropathy (NAION) mechanisms are unclear. We report a 28-year-old man with type 2 diabetes who developed right NAION 4–5 months after ...
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Safe use of fluorinated gases in vitreoretinal surgery: learning from patient safety incidents with expert panel recommendations from the British and Eire Association of ...

Background Errors in intravitreal fluorinated gas selection or dilution can result in unintended expansile concentrations, causing irreversible visual loss. We aimed to quantify the problem using ...
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Incidence of bilateral disease and choroidal neovascularisation in punctate inner choroiditis

Aims To characterise the incidence of bilateral involvement and choroidal neovascularisation (CNV) in punctate inner choroiditis (PIC). Methods Retrospective, single-centre case series of 52 patients ...
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Identifying patients with poor visual outcomes after primary rhegmatogenous retinal detachment surgery using machine learning

Aims To develop prediction models for identifying cases with poor visual outcomes after surgery for primary rhegmatogenous retinal detachment (RRD). Methods All data were obtained from the ...
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Maternal smoking during pregnancy: a risk factor for early childhood ophthalmologic conditions

Background/aims To investigate the association between maternal smoking during pregnancy and early childhood ophthalmologic conditions. Methods This population-based retrospective cohort study ...
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Choroidal vascular hyperpermeability and submacular haemorrhage in polypoidal choroidal vasculopathy: a multi-field ICGA analysis

Purpose To investigate the association between choroidal vascular hyperpermeability (CVH) and the occurrence of submacular haemorrhage (SMH) in polypoidal choroidal vasculopathy (PCV). Methods This ...
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Update on treatment and prophylaxis of herpes zoster ophthalmicus

Herpes zoster ophthalmicus (HZO) is a viral infection that affects the ophthalmic branch of the trigeminal nerve. HZO is potentially sight-threatening, affecting 4%–20% of all zoster cases. The ...