The Bacille Calmette-Guérin vaccine, formulated more than a century ago to protect people from tuberculosis, is also in use to prevent relapse in people who have had surgery for bladder cancer. If ...
Synapses in the hippocampus dwindle with age. Might a little-known, lipid-cleaving enzyme keep them from withering away? In the October 15 Nature Neuroscience, scientists led by Amar Sahay at Harvard ...
Digging deeper into the genetic causes of Alzheimer’s disease, some scientists are studying epigenetic regulation. In the October 12 Nature Aging, a group led by Jinying Zhao at the University of ...
Applications may request budgets of up to $1.5 million in direct costs per year; however, most awards are expected to be between $500,000–$900,000 in direct costs annually. Applications may request up ...
How much do blood-based biomarkers help in diagnosing Alzheimer’s disease? Quite a lot, according to scientists led by Albert Puig Pijoan and Marc Suárez-Calvet at the Hospital del Mar in Barcelona, ...
When it comes to new brain anatomy, clearance pathways seem to be the gift that keeps on giving. In a preprint posted September 27 on bioRxiv, scientists led by David Attwell at University College ...
Two groups of scientists have found that the same protein can have opposing effects on α-synuclein pathology. Microglia eliminate α-synuclein from neurons by “trogocytosis.” Silencing the glycoprotein ...
In the latest development on diagnostic methods for Alzheimer’s disease going mainstream, the U.S. Food and Drug Administration approved clinical use of Lantheus’ tau PET tracer florquinitau, aka ...
In the latest development on diagnostic methods for Alzheimer’s disease going mainstream, the U.S. Food and Drug Administration approved clinical use of Lantheus’ tau PET tracer florquinitau, aka ...
Also the 24th Alzheimer's Disease and Related Disorders Annual convention of the Dementia Society of the Philippines ...
The tau locus comes in two major genetic configurations, the H1 and H2 haplotypes. The latter carries a stretch of DNA, including the tau gene, that is flipped in orientation. As it turns out, a ...
Anti-amyloid immunotherapies come with a risk of serious brain hemorrhage, which can be mitigated via monitoring for amyloid-related imaging abnormalities (ARIA) via MRI scans. Early signs of edema ...
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