Drug Discovery & Development

Merck and Moderna’s cancer vaccine is customized for each patient’s tumor

A new investigational cancer vaccine developed by Merck & Co. and Moderna is customized based on the genome of each patient's ...
Drug Discovery & Development

The oral exposure challenge in PROTACs: What drug developers need to solve early

A WuXi AppTec director examines strategies for improving oral PROTAC exposure, from food-effect studies and linker design to ...
Drug Discovery & Development

AbbVie’s Maviret cured 96% of HCV trial participants. The real world is more complicated.

AbbVie's MAVYRET became the first of those antivirals cleared for acute infection in June 2025, with a 96% cure rate in trial ...
Drug Discovery & Development

Tufts model estimates 82x ROI and up to $21 million in value from Medable AI agent

Medable’s Pamela Tenaerts says “the CRA still needs to be there,” as she and Tufts’ Ken Getz explain how agents change ...
Drug Discovery & Development

FDA greenlights ViiV’s Tivicay PD for HIV-positive newborns in first month of life

The FDA has approved ViiV Healthcare’s Tivicay PD (dolutegravir) for treating HIV-1 in pediatric patients weighing at least 2 ...