Patriots running back TreVeyon Henderson won't play in the regular-season opener against the Seahawks, while the defending Super Bowl champions may have to begin their title defense without two of their top three safeties.

Keep a close eye on the transaction reports from Seattle to gauge the expected level of health of both players. Considering the Seahawks carried only three safeties on their initial 53-man roster, any practice squad elevations from the secondary could signal expected absences from one,