LYON, France — Researchers have, for the first time, successfully replaced the enzyme found in familial lecithin cholesterol acyltransferase (LCAT) deficiency using recombinant human LCAT ACP-501 ...
Scientists have determined the structure of the activated form of an enzyme that helps to return excess cholesterol to the liver, a study in eLife reports. The research reveals how a drug-like ...
摘要：肝细胞癌（HCC)是全球最常见的原发性肝癌，其代谢重编程以胆固醇代谢紊乱为关键特征。卵磷脂-胆固醇酰基转移酶（LCAT)参与HCC进展，但其确切的促癌机制尚不清楚。本研究旨在探究LCAT ...
Scientists have determined the structure of the activated form of an enzyme that helps to return excess cholesterol to the liver. Scientists have determined the structure of the activated form of an ...
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